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  • A unique gene expression signature is significantly differentially expressed in tumor-positive or tumor-negative sentinel lymph nodes in patients with melanoma

    A. Tarhini, Ahmad & Floros, Theofanis & Lin, Hui-Min & Lin, Yan & Rahman, Zahra & Ashraf, Madeeha & Vallabhaneni, Priyanka & Sander, Cindy & N.M. Rao, Uma & Panelli, Monica & LaFramboise, William & Kirkwood, John. August 2017, DOI: 10.1097/CMR.0000000000000383 Abstract The purpose of this study was to learn whether molecular characterization through gene expressionRead more

    • 1 Αυγούστου 2017
  • Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non–small cell lung cancer

    Ahmad A. Tarhini MD, PhD, Imran Rafique MDDS, Theofanis Floros MD, Phu Tran MD, William E. Gooding MS, Liza C. Villaruz MD, Timothy F. Burns MD, PhD, David M. Friedland MD, Daniel P. Petro MD, Mariya Farooqui PhD, Jose Gomez-Garcia PhD, Autumn Gaither-Davis BS, MPH, Sanja Dacic MD, PhD, Athanassios Argiris MD, Mark A Socinski MD, Laura P. Stabile PhD, Jill M. Siegfried PhD First published: 4 MayRead more

    • 4 Μαΐου 2017
  • Multidisciplinary Management of Gastrointestinal Cancers

    ISBN: 978-981-4651-87-5 This invaluable book provides an introduction to the development and application of molecular biology with a focus on translational research development in a variety of gastrointestinal cancers. Multidisciplinary Management of Gastrointestinal Cancers will emphasize the multidisciplinary aspects of GI cancer diagnosis, treatment and management, introduce the application of new techniques in GI cancerRead more

    • 1 Οκτωβρίου 2016
  • A tumor and immune related miRNA signature predicts progression-free survival of melanoma patients treated with ipilimumab

    Ahmad Tarhini, Priyanka Vallabhaneni, Theofanis Floros, William A. LaFramboise, Panayiotis V. Benos and Lucas Santana dos Santos. DOI: 10.1158/1538-7445.AM2016-473 Published July 2016 Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA   Abstract Background Patients with regionally advanced melanoma were treated with neoadjuvant ipilimumab in a previously reported study (Tarhini et al, PLOS One 2014). MicroRNA (miRNA) expression profiles of tumors of treated patients were investigated forRead more

    • 17 Μαρτίου 2016
  • Anticancer Cytokines: Biology and Clinical Effects of Interferon-α2, Interleukin (IL)-2, IL-15, IL-21, and IL-12

    Seminars in Oncology Volume 42, Issue 4, August 2015, Pages 539-548 Theofanis Floros, Ahmad A. Tarhini DOI: http://dx.doi.org/10.1053/j.seminoncol.2015.05.015 Abstract Efforts over nearly four decades have focused on ways to use cytokines to manipulate the host immune response towards cancer cell recognition and eradication. Significant advances were achieved with interleukin-2 (IL-2) and interferon-α (IFN-α), primarily inRead more

    • 1 Αυγούστου 2015
  • Downstaging of a Gastroenteropancreatic Neuroendocrine Tumor after Combination Therapy of Temozolomide, Bevacizumab and Long-Acting Somatostatin Analogs

    S. Antoniou, G. Kanakis, A. Zilos, D. Thomas, N. Tzavaris, A. Ntokou, Theofanis Floros, A. Koumarianou, G. Kaltsas Introduction Patients with gastroenteropancreatic endocrine (GEP) tumors and progressive disease have been treated with several chemotherapeutic regimens with variable responses and considerable toxicity. Recent studies have shown that GEP tumors may respond to therapy with anti-angiogenic agents, mainly as a result of their increased vascularity.Read more

    • 1 Ιουλίου 2010
  • Gastric Metastases Originating from Breast Cancer: Report of 8 Cases and Review of the Literature

    Anticancer Research November 2009 vol. 29no. 11 4759-4763 D. PECTASIDES, A. PSYRRI, K. PLIARCHOPOULOU, T. FLOROS, G. PAPAXOINIS, M. SKONDRA, G. PAPATSIBAS, A. MACHERAS, G. ATHANASAS, P. ARAPANTONI-DATIOTI and T. ECONOMOPOULOS Abstract Background: Breast cancer metastasis to the stomach is rare. It is very important to distinguish a breast cancer metastasis to the stomach from a primaryRead more

    • 29 Νοεμβρίου 2009
  • Combination Chemotherapy with Docetaxel, Vinorelbine and Estramustine Phosphate in Metastatic Androgen-resistant Prostate Cancer: A Single Institution Experience

    Anticancer Research February 2009, vol. 29 no. 2 769-775 DIMITRIOS PECTASIDES, EIRINI PECTASIDES, GEORGE PAPAXOINIS, ANNA KOUMARIANOU, AMANDA PSYRRI, NIKOLAOS XIROS, NIKOLAOS TOUNTAS, KONSTANTINOS KAMPOSIORAS, GEORGE PAPATSIBAS, THEOFANIS FLOROS, PANAGIOTIS GOUVERIS, SOFIA KARAGEORGOPOULOU and THEOFANIS ECONOMOPOULOS Abstract The aim of this study was to evaluate the activity and toxicity of docetaxel, vinorelbine and oral estramustine inRead more

    • 1 Μαρτίου 2009
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